A novel application of BIFC in studying the topology of polytopic proteins

【Author】

Fei Dou;Xingya Chang;

【Abstract】

<正>Bimolecuiar Fluorescence Complementation assay is very useful to detect protein-protein interaction.Here,instead of studying two proteins interaction, we report a novel application of BiFC in studying the topology of proteins with multi trans-membrane domains. Presenilinl is a critical component of the gamma-secretase complex.But its

【Keywords】

A novel application of BIFC in studying the topology of polytopic proteins;

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