Design of genetically encoded biosensors for rapid profiling and imaging of enzymatic functions

【Author】

Seung-Goo Lee;Kil-Kwang Kwon;Soo-Jin Yeom;Hyewon Lee;

【Abstract】

<正>Synthetic biology inspires new engineering principles of biological systems,yielding new transferable bio-parts,advanced bio-devices,and artificial cellular systems.We applied this approach for the creation of rapid and sensitive tools to monitor important enzymes in living cells,specific metabolites,and protein-protein interactions.So far,we were successful in developing i)Lego-like assembly of fluorescent

【Keywords】

profiling;biosensors;creation;assembly;cytometry;enzymatic;yielding;encoded;monitor;enzymes;

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