Novel enzyme discovery through examination of archaeal metabolism

【Author】

Haruyuki Atomi;Yuki Makino;Hiroki Kawamura;Shin-ichi Hachisuka;Ryo Takeno;Takaaki Sato;

【Abstract】

<正>The Archaea represent the third domain of life and are phylogenetically distinct to the Bacteria and Eucarya.Archaea harbor a number of metabolic pathways that differ from previously recognized,classical pathways identified in bacteria and eukaryotes.Examination of archaeal metabolism has thus led to the discovery of many novel enzymes and metabolic pathways.Until now,we have focused on the metabolism of the hyperthermophilic archaeon Thermococcus kodakarensis.This organism displays an optimal growth

【Keywords】

metabolism;Bacteria;harbor;enzymes;disruption;partitioning;chromosome;serine;coenzyme;nucleoside;

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