Engineering of protein folding based on beta-turn code

【Author】

Bharat Madan;Sun-Gu Lee;

【Abstract】

<正>Beta-turns in beta-hairpins,which are generally found on a protein surface,are a common structural feature in protein structures that play a key role in reversing the direction of the polypeptide chain and forming the compact globular state of a protein.In addition,they often play a variety of functional roles in proteins,such as the binding sites in antibodies and active sites of enzymes.Over the past two decades,the

【Keywords】

folding;turns;residue;polypeptide;hairpin;modulating;mutant;predominantly;favorable;restore;

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