Comparative genomic,transcriptomic and secretomic profiling of Penicillium oxalicum HP7-1 and its cellulase and xylanase hyper-producing mutant EU2106,and identification of two novel regulatory genes of cellulase and xylanase gene expression

【Author】

Shuai Zhao;Yu-Si Yan;Qi-Peng He;Lu-Sheng Liao;Long Wang;Bo Ma;Cheng-Xi Li;Ya-Ru Xiong;Ting Zhang;Mei-Yuan Zhang;Gui-Yan Liao;Li-Chun Mao;Qing-Dong Nong;Jun-Liang Liu;Cheng-Jie Duan;Jia-Xun Feng;

【Abstract】

<正>Comparative omics approaches can support rational genetic engineering and/or breeding of filamentous fungi with improved cellulase production capacity.A 30.62 Mb of Penicillium oxalicum HP7-1genome was sequenced,and 9834 protein-coding genes were annotated.Re-sequencing of the cellulase hyper-producing mutant EU2106 genome identified 274 single nucleotide variations and 12Insertion/deletions.Comparative genomic,transcriptomic and secretomic profiling of Penicillium oxalicum HP7-1 and EU2106 revealed four candidate regulators of cellulase and xylanase gene expression.Deletion

【Keywords】

profiling;Penicillium;genomic;mutant;sequenced;sequencing;breeding;producing;fungi;candidate;

References

To explore the background and basis of the node document

Springer Journals Database

Total: 0 articles

Similar documents

Documents that have the similar content to the node document

Springer Journals Database

Total: 0 articles