Discovery of a novel teichoicase and its enzymatic characteristics

【Author】

Sen Yang;Gao Lei;Xinyu Liu;Guoqing Xia;Hongge Chen;

【Abstract】

<正>Teichoic acids are important components of Gram-positive bacterial cell wall and constitute roughly50%of wall mass[1].The genetics and biosynthesis of wall teichoic acid have been extensively studied,however comparatively little is known regarding the enzymatic degradation of this biological polymer.Though early in 1972 teichoicase,a kind of phosphodiesterases,which could degrade the backbone of teichoic acids specifically,was proposed and the teichoicase activity was demonstrated to exist in a

【Keywords】

enzymatic;backbone;degrade;genetics;constitute;biosynthesis;Acinetobacter;bacterium;roughly;specifically;

References

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Total: 6 articles

  • [1] Edmund M. Wise, Jr.;;Rhona S. Glickman;;Ellen Teimer, Teichoic Acid Hydrolase Activity in Soil Bacteria, Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences of the United States of America (Proceedings of the National Academy of Sciences of the United States of America)
  • [2] Sewell EW;Brown ED, Taking aim at wall teichoic acid synthesis:new biology and new leads for antibiotics, J Antibiot (Tokyo), Journal of Antibiotics (Journal of Antibiotics)
  • [3] Edmund M. Wise, Jr.;;Rhona S. Glickman;;Ellen Teimer, Teichoic Acid Hydrolase Activity in Soil Bacteria, Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences of the United States of America (Proceedings of the National Academy of Sciences of the United States of America)
  • [4] Sewell EW;Brown ED, Taking aim at wall teichoic acid synthesis:new biology and new leads for antibiotics, J Antibiot (Tokyo), Journal of Antibiotics (Journal of Antibiotics)

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