Structure-guided directed evolution of a novel cyclohexylamine oxidase from Brevibacterium oxydans IH-35A

【Author】

Rui Gong;Peiyuan Yao;Qiaqing Wu;Dunming Zhu;

【Abstract】

<正>Cyclohexylamine oxidase(CHAO)is a flavoprotein which has been used to deracemize of primary,secondary and tertiary amines in part of chemoenzymatic oxidation-reduction cycle.The deracemization process involves a two-step,one-pot reaction and employs an enantioselective amine oxidase in combination with a non-selective chemical reducing agent(Fig.1).The limited substrate scope,insufficient

【Keywords】

guided;insufficient;cycle;tertiary;amines;directed;allyl;iterative;screening;saturation;

References

To explore the background and basis of the node document

Springer Journals Database

Total: 0 articles

Similar documents

Documents that have the similar content to the node document

Springer Journals Database

Total: 0 articles