Comparison study of various signal sequences and secretion production of L-asparaginase in Corynebacterium glutamicum

【Author】

Jin-Young Lee;Hak-Sung Kim;Jin-Ho Lee;Geun-Joong Kim;

【Abstract】

<正>L-asparaginase(L-asparagine amidohydrolase;EC3.5.1.1)catalyze the conversion of L-asparagine to L-aspartic acid and ammonia which typically used for the treatment of acute lymphoblastic leukemia(ALL)in pharmaceutical industry and for the prevention of acrylamide formation in food industry as a food processing aid.Various case studies have been attempted to optimize the production under diverse

【Keywords】

secretion;acrylamide;pharmaceutical;lymphoblastic;ammonia;diverse;attempted;aspartic;optimize;catalyze;

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