The efficacy of stereotactic body radiotherapy for patients with hepatocellular carcinoma


Hongzhen Zhang1,Yazhen Wang1,Ning Xu2,Xinbo Duan1,Chaoying Ren1 1 Department of Radiology,Hebei Province People's Hospital,Shijiazhuang 050051,China 2 The Hebei University of Science and Technology,Shijiazhuang 050051,China


Objective:To evaluate efficacy of the stereotactic body radiotherapy for patients with hepatocellular carcinoma. Methods:Twenty-seven patients with hepatocellular carcinoma were treated by technique of stereotactic body radiotherapy. Planning of treatment was made and the prescribed dose was adjusted depending on the site of the tumor,clinical target volume(GTV),Kanofsky Performance and aim of treatment.Planning target volume received 50%–80%of the prescribed dose for 3.2–4.2 Gy per-fraction.Treatment total dose was 32–42 Gy(median dose 40 Gy)in daily fractions of 3.2–4.2 Gy for five fractions one week.Results:All the patients completed the planned radiotherapy.The tumor response rate was CR 25.9%,PR 55.6%,NR 18.59%;the response rate(CR+PR)was 81.5%.Half-year local recurrence-free survival rate was 75%;1-year local recurrence-free survival rate was 22%.There were no serious complications during radiotherapy and follow- up.Pain relieve rate in liver region was 83.3%.Conclusion:Stereotactic body radiotherapy can improve the local control and quality of life on the treatment of primary hepatic neoplasm while not increasing the treatment complication.


hepatoma;hepatocellular carcinoma;radiotherapy;stereotactic body radiotherapy;prognosis


To explore the background and basis of the node document

Springer Journals Database

Total: 10 articles

  • [1] LIANG Shi-xiong, JIANG Guo-liang, ZHOU Zhen-hua ,et al(Department of Radiati on Oncology, Cancer Hospital, Fudan University, Shanghai 200032, China), A phase Ⅰ/Ⅱ clinical trial of three dimensional conformal radiation therapy combined with transcatheter arterial chemoembolization for liver cancer, China Oncology,
  • [2] LI Yu , YAN Ying , ZHANG Hai-bo,GUO Zhan-wen,YAN Zi-cai ,LI Dong. Department of Radiation Oncology,General Hospit al , the PLA Shenyang Military Region , Shenyang 110015,China, Three-dimensional conformal radiation combined with transarterial chemoemboliza t ion for unresectable primary liver cancer, Chinese Journal of Radiation Oncology,
  • [3] Jason Chia-Hsien Cheng;;Jian-Kuen Wu;;Patricia Chiao-Tzu Lee;;Hua-Shan Liu;;James Jer-Min Jian;;Yu-Mong Lin;;Juei-Low Sung;;Gwo-Jen Jan, Biologic susceptibility of hepatocellular carcinoma patients treated with radiotherapy to radiation-induced liver disease, International Journal of Radiation Oncology, Biology, Physics,
  • [4] Yang BH;Xia JL, Standardization of clinical diagnosis and staging inhepatocellular carcinoma, Chin J Hepatol, Chinese Journal of Hepatology (Chinese Journal of Hepatology)


Similar documents

Documents that have the similar content to the node document

Springer Journals Database

Total: 43 articles