Inhibitory effects of asiaticoside on nitric oxide production in neonatal rat microglia cultures

【Author】

QI Li-Hong, WANG Bao-Kui DU Ze-Ying, LI Xiao-Yu ( Dong Fang Hospital, Fuzhou 350001, China, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China)

【Abstract】

<正> Asiaticoside, one or the components extracted from Centella asiatica (L) Urban which has anti-viral and anti-inflammatory actions, was studied on nitric oxide (NO) production from primary cultured rat microglia in vitro. NO concentration was represented by nitrite and determined by Oriess reaction. Asiaticoside did not show any inhibiton on NO production in resting microglia,but significantly decreased its levels in lipoplysaccharides-stimulated rat microglia at the concentration 10

【Keywords】

Inhibitory effects of asiaticoside on nitric oxide production in neonatal rat microglia cultures;

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