Sex steroids differentially modulate mitochondrial function in male rat brain

【Author】

Ali Razmara;Vincent Procaccio;Diana N.Krause;Sue P.Duckies;

【Abstract】

<正>As fundamental energy-producing units, mitochondria play an important role in reactive oxygen species (ROS) production. There is increasing evidence for mitochondrial dysfunction and ROS production as key underlying mechanisms for the development of age-related diseases. We have shown that the gonadal steroids, estrogen (E) and testosterone (T), have opposing effects on inflammation in brain blood vessels, but knowledge of the impact of these sex hormones on

【Keywords】

Sex steroids differentially modulate mitochondrial function in male rat brain;

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