Mechanisms of myogenic tone and roles of tyrosine kinases, integrin receptors and microvascular control

【Author】

Michael A.Hill;Timothy V.Murphy;Luis Martinez-Lemus;Gerald A.Meininger;

【Abstract】

<正>Arterioles exhibit a state of partial constriction that is related to the level of intraluminal pressure. This vasomotor response is a property of vascular smooth muscle and occurs independently of direct neurohumoral and endothelial input. The physiological relevance of myogenic constriction relates to the setting of peripheral resistance, local autoregulatory ability, provision of a level of tone that vasodilators can access, and a contribution to the regulation of capillary pressure. Despite its importance in the regulation of microvascular haemodynamics the exact

【Keywords】

Mechanisms of myogenic tone and roles of tyrosine kinases,integrin receptors and microvascular control;

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