Role of P2X receptors in autoregulation of renal blood flow

【Author】

Edward W.Inscho;

【Abstract】

<正>Autoregulation of renal blood flow is an established physiological phenomenon, however the signaling mechanisms involved remain elusive.Autoregulatory adjustments in preglomerular resistance involve myogenic and tubuloglomerular feedback influences. While there is general agreement on the participation of these two regulatory pathways, the signaling molecules and effector mechanisms have not been identified. Currently, there a two major hypotheses being considered to explain the mechanism by which tubuloglomerular feedback signals are transmitted from the macula densa to the afferent arteriole. The adenosine hypothesis proposes

【Keywords】

Role of P2X receptors in autoregulation of renal blood flow;

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