Flow, pressure and vascular responsiveness


Lasse E.Rasmussen;Paul M.Vanhoutte;Boye L.Jensen;Ole Skott;


<正>Unidirectional endothelial shear stress is supposed to maintain a continuous release of nitric oxide.[1-3]. Consistent with this, low wall shear stress is associated with endothelial dysfunction in patients with peripheral artery disease or abdominal aortic aneurysm[4]. However in rabbit aorta perfused ex vivo [5] chronic shear stress does not stimulate eNOS. . Thus, the effect of flow on endothelial function in large vessels is unresolved. Therefore experiments were


Flow,pressure and vascular responsiveness;


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Total: 6 articles

  • [1] Yamawaki et al, Circulation, Circulation (Circulation)
  • [2] Boo et al, J Biol Chem, Journal of Biological Chemistry (Journal of Biological Chemistry)
  • [3] Dimmeler et al, Nature, Nature (Nature)
  • [4] Jin et al, Circ Res, Circulation Research (Circulation Research)


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