Signaling role of NAOPH oxidase 4 in cardiovascular system

【Author】

Michael Kirber;John F.Keaney;

【Abstract】

<正>NADPH oxidase is a major source of intracellular reactive oxygen species (ROS) and NADPH oxidase 4 (Nox4) represents a major isoform in both vascular cells and cardiomyocytes. Emerging evidence indicates that ROS serve a number of functions in cardiovascular system in both normal and pathologic circumstances. Current evidence supports a role for ROS as a generalized "injury" response in cardiovascular system. This contention is supported by

【Keywords】

Signaling role of NAOPH oxidase 4 in cardiovascular system;

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