Cerebral neurogenic nitrergic vasodilation: effects of ChEls


TJF Lee;M Mozayan;


<正>Morphological and pharmacological studies have demonstrated the presence of functional sympathetic-parasympathetic interaction in regulating cerebral vascular tone. Activation by nicotine of sympathetic nerves results in release of norepinephrine which then diffuses to act on presynapticβ2-adrenoceptor located on the neighboring nitrergic nerve terminals to release nitric oxide (NO) causing vasodilation. On the other hand, acetylcholine released in cerebral


Cerebral neurogenic nitrergic vasodilation;nAChR;


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