Vasorelaxing and pro-angiogenic effects of endothelial beta3-adrenoceptors

【Author】

C.Dessy;B.Rozec;K.Jnaoui;P.Ghisdal;O.Feron;J-L Balligand;

【Abstract】

<正>The existence of a rich sympathetic innervation of the coronary arteries raises the importance of catecholamines as endogenous modulators of myocardial perfusion, in addition to their direct inotropic effects. Classically, adrenergic coronary yasodilation has been ascribed to β1-and β2-adrenoceptor stimulation coupled to increases in smooth muscle cAMR.In addition, we demonstrated the expression of β3-adrenoceptor mRNA and protein in extracts of human

【Keywords】

Vasorelaxing and pro-angiogenic effects of endothelial beta3-adrenoceptors;

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