Is endothelium-derived hyperpolarizing factor a therapeutic drug target?

【Author】

Michel Félétou;Paul M.Vanhoutte;

【Abstract】

<正>The endothelium controls vascular tone not only by releasing NO and prostacyclin but also by other pathways causing hyperpolarization of the underlying smooth muscle cells. This characteristic was at the origin of the denomination endothelium-derived hyperpolarizing factor (EDHF). It is now obvious that this acronym includes different mechanisms. In general, EDHF-mediated responses involve an increase in the intracellular calcium concentration via the

【Keywords】

EDHF;Is endothelium-derived hyperpolarizing factor a therapeutic drug target;

References

To explore the background and basis of the node document

Springer Journals Database

Total: 0 articles

Similar documents

Documents that have the similar content to the node document

Springer Journals Database

Total: 0 articles