Profound bioenergetic abnormalities in peri-infarct myocardial regions and its response to stem cell transplantation

【Author】

Jianyi Zhang Cardiology, University of Minnesota Medical School, USA

【Abstract】

<正>Regions of myocardial infarct (MI) are surrounded by a border zone (BZ) of normally perfused but dysfunctional myocardium. Although systolic dysfunction has been attributed to elevated wall stress in this region,there is evidence that intrinsic abnormalities of contractile performance exist in BZ myocardium. This study examined whether decreases of high energy phosphates (HEP) and mitochondrial F1F0-ATPase (mtATPase) subunits typical of failing myocardium exist

【Keywords】

stem;Profound bioenergetic abnormalities in peri-infarct myocardial regions and its response to stem cell transplantation;BZ;cell;

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