Gonadal hormones and mitochondrial function:A new paradigm for vascular protection?

【Author】

Sue Piper Duckies;Diana N.Krause;Vincent Procaccio;

【Abstract】

<正>Estrogen protects against cardiovascular disease in animal models, but recent prospective clinical trials of hormone replacement therapy in the United States and Great Britain have not shown beneficial cardiovascular effects. One explanation of this discrepancy is that women in these studies were 10 years or more past the menopause. Estrogen may protect against cardiovascular disease, but be unable to reverse existing disease. Loss of mitochondrial

【Keywords】

Gonadal hormones and mitochondrial function;

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