Regulation of cardiovascular stem cell survival and differentiation by cholesterol-lowering therapy

【Author】

Yong-Jian Geng University of Texas Houston Medical School and Texas Heart Institute, Houston, TX, USA

【Abstract】

<正>Cholesterol serves as an important component in the lipid layers of plasma membrane. Synthesis of this sterol compound is required for the development of embryonic tissues. However, under various pathological conditions, especially atherosclerosis, overproduced cholesterol may damage tissue cells and trigger apoptosis. Attenuation of stem cell function may occur in atherosclerosis. In this study, we explored the potential role of the cholesterol lowering

【Keywords】

stem;Regulation of cardiovascular stem cell survival and differentiation by cholesterol-lowering therapy;cell;

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