Mouse models for restrictive cardiomyopathy due to cTnl mutation and cTnl deficiency

【Author】

Xupei Huang Department of Biomedical Science, Center for Molecular Biology and Biotechnology, Florida Atlantic University, Boca Raton, FL 33431, USA

【Abstract】

<正>Cardiomyopathies are the disorders primarily affect cardiac muscles associated with cardiac dysfunction. On the ground of their morphology and pathophysiology, Cardiomyopathies may be classified into three major types: hypertrophic cardiomyopahty (HCM), dilated cardiomyopathy (DCM) and restrictive cardiomyopathy (RCM). Cardiac troponin I (cTnI) mutations have been linked to the development of restrictive cardiomyopathy in human patients. We have created two

【Keywords】

cTnI;Mouse models for restrictive cardiomyopathy due to cTnI mutation and cTnI deficiency;

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