Protective role of coronary endothelium during the development of cardiac hypertrophy

【Author】

David D.Ku;

【Abstract】

<正>The importance of coronary endothelium in the modulation of the underlying vascular smooth muscle function in health and disease is well documented. Extensive experimental reports have shown that coronary endothelial dysfunction could contribute to and worsen the development of cardiovascular diseases, such as ischemic/reperfusion injury, hypercholesterolemia, diabetes, hypertension and heart failure. However, the protective role of coronary endothelium especially during the early phases of cardiovascular disease has not been well studied. We recently reported that monocrotaline (MCT)-induced pulmonary hypertension (PH) in rats was

【Keywords】

RVH;Protective role of coronary endothelium during the development of cardiac hypertrophy;

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