Comparison of different dose combination of telmisartan and amiodipine in the control of SBP in spontaneously hypertensive rats

【Author】

Menq Zheng,XiYong Yu, YongHeng Fu & ShuGuang Lin Research Center of Medical Sciences, Guangdong Provincial People's Hospital

【Abstract】

<正>Objectives: To explore a new compound preparation for anti-hypertension more effective and safely. Methods: Experiments were conducted on male spontaneously hypertensive rats (SHR). At 14 weeks of age with weight of 190-200 gram, 48 SHR, whose tail arterial SBP is more than 140 mmHg, were randomly divided into 6 groups: (1) An untreated group; (2) Low-low dose combination: treated with low dose of amlodipine(0.225mg/kg/day, Aml-L) and low dose of

【Keywords】

hypertension, amlodipine, telmisartan

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