Hypoxia-induced endotheliat dysfunction in human umbilical vein endothelial cells

【Author】

L.■stergaard;U.Simonsen;E.Stankevicius;T.Ledet;M.R.Andersen;H.Vorum;M.J.Mulvany;

【Abstract】

<正>Several pathologies either results in or from hypoxia. This includes i.e. chronic obstructive lung disease, cancer and ischemic reperfusion injury. The endothelial cells are the first to encounter a lowering in the blood oxygen saturation and since they highly influence for example the vascular tone but also many other responses, these cells are obvious candidates for studying the effects of hypoxia on blood vessels.

【Keywords】

eNOS;Hypoxia-induced endothelial dysfunction in human umbilical vein endothelial cells;

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