Expression of urocortin in rat lung and its effect on pulmonary vascular permeability


Yuqing Wu, Yinyan Xu, Hong Zhou & Shengnan Li Department of Pharmacology, Nanjing Medical University


<正>Urocortin (UCN), a newly identified 40-amino acid corticotropin-releasing hormone (CRH) structurally related peptide, has been demonstrated to be expressed in central nervous system and many peripheral tissues of rats and humans. The aim of this study was to investigate the expression profile of UCN in rat lung and the effect of UCN on lung vascular permeability. The expression of UCN mRNA was detected by reverse transcriptase-polymerase chain reaction


urocortin,rat, lung, pulmonary vascular permeability


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