Involvement of cGMP-dependent protein kinase in relaxation of porcine cardiac veins induced by nitroglycerin and nitric oxide

【Author】

Hui Qi,Xue Qin & Yuansheng Gao Dept. of Physiology & Pathophysiology, Peking University Health Science Center, Beijing, 100083, China

【Abstract】

<正>Objectives: Cardiac veins have long been seen primarily as conduit vessels that have little vasoactivity. However, increasing evidence indicates that cardiac veins of a number species exhibit significant vasoactivity in response to various constrictors and dilators and may actively contribute to the regulation of coronary circulation. Recently, it has been found that cardiac venous tension is modulated by endothelium-derived nitric oxide under basal conditions and when stimulated. Since cGMP-dependent protein kinase (PKG) is involved in mediating

【Keywords】

Involvement of cGMP-dependent protein kinase in relaxation of porcine cardiac veins induced by nitroglycerin and nitric oxide;cGMP;

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