Asymmetric dimethylarginine enhances tissue factor coagulating pathway: implications for the pathophysiology of acute coronary syndromes

【Author】

De-Jian Jiang,Yu Cao,Hong-Ya Xin,Su-Jie Jia & Yuan-Jian Li Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China; Department of Cardiology, The Third Xiangya Hospital of Central South University, Changsha 410013, China;Department of Hematology, Xiangya Hospital of Central South University, Changsha 410078, China

【Abstract】

<正>Background and objective: Endothelial dysfunction is recognized as an early event in the patnpgenesis of atherosclerosis. Asymmetric dimethylarginine (ADMA), a major endogenous inhibitor of nitric oxide synthase, can induce endothelial dysfunction and atherogenesis. Some recent clinical studies suggest that the high circulating level of ADMA is an independent risk factor for coronary artery diseases (CAD) and involved in the development of acute coronary

【Keywords】

ADMA;HUVECs;Asymmetric dimethylarginine enhances tissue factor coagulating pathway;ACS;

References

To explore the background and basis of the node document

Springer Journals Database

Total: 0 articles

Similar documents

Documents that have the similar content to the node document

Springer Journals Database

Total: 0 articles