Critical roles for chemokine SDF-1 signaling in the development of growth plate chondrocyte hypertrophy

【Author】

Katsuaki Kanbe;Richard Terek;

【Abstract】

<正>Objective:To determine whether the SDF-1/CXCR4 axis plays a role in regulating chondrocyte hypertrophy,and if so,what its underlying molecular mechanism is. Methods:Myc-tagged retro-viral vector RCAS encoding full length chicken CXCR4(RCAS/CXCR4),or RCAS alone was transfected

【Keywords】

SDF;Critical roles for chemokine SDF-1 signaling in the development of growth plate chondrocyte hypertrophy;CXCR;

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