Antigen cross presentation and T cell activation by dendritic cells

【Author】

Sebastian Amigorena;

【Abstract】

<正>Dendritic cells represent a highly specialized hematopoietic lineage,whose main role is to sense infections in tissues and to activate specific T lymphocytes in lymphoid organs to mount immune responses adapted to the threat.To activate T lymphocytes,dendritic cells need to present peptides derived from infectious antigens on MHC molecules on their plasma membrane.There are two main

【Keywords】

presentation;specialized;activate;hematopoietic;lymphoid;threat;mount;Antigen;organs;infectious;

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