Revisiting the importance of CD1a on Langerhans cells

【Author】

Florian Winau;

【Abstract】

<正>In contrast to conventional T cells that recognize peptides on MHC proteins,CD1molecules present lipid antigens to T lymphocytes.The abundant expression of CD1a hallmarks Langerhans cells in the skin,a subtype of dendritic cell(DC)with antigen-presenting functions.CD1a can bind and display a broad spectrum of lipid antigens derived from exogenous sources,such as bacteria,or host origin.The

【Keywords】

Langerhans;recognize;abundant;exogenous;lipid;subtype;overcome;transgenic;inflammation;extrinsic;

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