Integration of costimulatory signals by T cells

【Author】

Susanne Heinzel;

【Abstract】

<正>T cells receive a multitude of signals upon their activation by APC.While most of these signals are well described,little is known how each of these signals work together to control the response magnitude.In response to the antigenic and costimulatory activation,T cells typically undergo 5-20 divisions.Recent studies(Marchingo JM,Science 2014)have shown that the type and strength of the

【Keywords】

antigenic;magnitude;typically;automatically;resting;entering;links;qualitative;presentation;programs;

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