Modulation of immunity by dendritic cells in cancer


Nina Bhardwaj;


<正>Innate immune cells such as dendritic cells can be profoundly impacted in advanced cancers.This can lead to their dysfunctional activity and consequently compromised anti-tumor immunity.Alternatively,the tumor microenvironment can support DC activation through a number of mechanisms that involve their local activation through the production of tumor associated nucleic acids.Novel mechanisms that imprint DC to either subvert or activate adaptive immune responses will be




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