Intestinal CD103+SIPRa- cross presenting dendritic cells are absent in human fetal gut

【Author】

Kaijun Liu;Yuri Souwer;Toni M.M.van Capel;Esther W.M.Taanman-Kueter;Bianca Blom;Esther C.de Jong;

【Abstract】

<正>BACKGROUND&AIMS:Intestinal dendritic cells(DCs)are the key regulator to maintain mucosal integrity.The maturation and development of the intestinal immune system are highly influenced by microbiota.The characterization of fetal intestinal DCs,which has not exposed to microbiota yet,is still unknown.We aim to characterize the DC subsets in fetal gut.METHODS:Human fetal intestinal DC subsets were sorted by flow cytometry.The

【Keywords】

fetal;cytometry;maturation;maintain;AIMS;exposed;characterize;absent;regulator;mucosal;

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