CD16+ dendritic cells are a unique myeloid antigen presenting cell population

【Author】

Phillip Fromm;Michael Papadimitrious;Jennifer Hsu;Fiona Kupresanin;Ben Kong;Kenneth Bradstock;Stephen Larsen;John Gibson;Georgina Clark;Derek Hart;

【Abstract】

<正>Dendritic Cells(DC)are identified phenotypically in human blood as HLA-DR+cells,which lack major cell surface lineage markers.As part of the recent Human Leucocyte Differentiation Antigen Workshop,we demonstrated that fresh human blood myeloid antigen presenting cells including monocytes and DC display a continuum of CD14 and CD16 expression.This limits the robustness of accurate DC

【Keywords】

myeloid;robustness;Antigen;limits;fresh;lineage;kinetics;continuum;populations;cytometry;

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