PDC-stimulative lactic acid bacteria strain enhances antigen-specific immune responses

【Author】

Hiroaki Suzuki;Kenta Jounai;Konomi Ohshio;Toshio Fujii;Daisuke Fujiwara;

【Abstract】

<正>Lactic acid bacteria(LAB)have beneficial effects on protective immunity against pathogens by activating innate immune responses.However,little is known about whether LAB contribute to antigen-specific immune responses via dendritic cell(DC).We previously reported that Lc.lactis JCM 5805(JCM5805)stimulates plasmacytoid dendritic cell(p DC)to produce large amounts of IFN-alpha.Because p DC links

【Keywords】

activating;lactic;immunity;innate;protective;links;cytotoxic;vaccine;stimulated;maturation;

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