Unbiased study of the DC – T cell interactome in the antigen-challenged lymph node

【Author】

Caterina Curato;Amir Giladi;Diego Adhemar Jaitin;Eva Zupancic;Eyal David;Helena Florindo;Ido Amit;Steffen Jung;

【Abstract】

<正>Dendritic cells(DC)are unrivalled in their potential to prime naive T cells by presenting antigen and providing co-stimulation.Moreover,DC decode antigen context by virtue of pattern-recognition receptors,such as TLRs and CLRs,and their T cell polarization through instructive signals in form of distinct secreted cytokines.The diversity of polarized T helper cells in the in vivo context has been explored in

【Keywords】

providing;virtue;stimulation;secreted;naive;polarized;helper;TLRs;cytokines;isolation;

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