Characterization of human clinical grade tolerogenic dendritic cells used in the one study clinical trial

【Author】

Aurélie Moreau;Laurence Bouchet-Delbos;Cédric Louvet;Amy Managh;Gaelle Bériou;Véronique Daguin;Virginie Vignard;Barry Sharp;Bernard Vanhove;Nathalie Labarriere;Régis Josien;Gilles Blancho;Maria-Cristina Cuturi;

【Abstract】

<正>Protective potential of rodent tolerogenic dendritic cells(DCs)to control immune responses was demonstrated in models of autoimmunity and transplantation.Due to this success,cell therapy arises today as a promising strategy to treat patients suffering from autoimmune disease or receiving a graft.To this aim,we developed a GMP-compliant manufacturing process to derive in a GM-CSF dependent manner

【Keywords】

compliant;autoimmune;graft;today;rodent;manner;suffering;receiving;currently;transplant;

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