Identification of novel human epidermal dendritic cell populations


Kirstie Bertram;Rachel Botting;Hafsa Rana;Heeva Baharlou;Kerrie Sandgren;Anthony Cunningham;Andrew Harman;


<正>Human skin epidermis is considered to contain a single dendritic cell(DC)population called a Langerhans cell(LC).LCs can be identified by their high surface expression levels of HLA-DR,CD1a and the C-type lectin receptor(CLR)langerin.However using flow cytometry we have observed two additional CD1a+cells that have not been previously described.




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