Ebola virus infects CD11b+ DCs but not CD103+ DCs in vivo

【Author】

Anja Lüdtke;Lisa Oestereich;Paula Ruibal;Stephan Günther;Juliana Idoyaga;César Mu?oz-Fontela;

【Abstract】

<正>Ebolaviruses(EBOV)are zoonotic RNA viruses from the Filoviridae family and the causative agent of Ebola virus disease(EVD)in humans and non-human primates(NHPs).Between 2014 and 2015,EBOV has caused the biggest documented outbreak in West Africa with 28,639 total cases and 11,316 deaths.Due to the lack of immunocompetent small animal models and the restriction of EBOV research to

【Keywords】

deaths;Africa;outbreak;pathogenesis;RNA;dissemination;immunity;depletion;monocyte;kinetics;

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