Interplay among lung dendritic cell subsets during allergic airway inflammation

【Author】

Shuying Yi;Rui Niu;Guangming Zhu;Hao He;Jianguo Liu;Xiuli Jing;Wengang Song;Hua Tang;

【Abstract】

<正>Dendritic cells(DCs)are crucial for mounting allergic airway inflammation,but it is unclear whether and how lung DC subsets work in concert to modulate eosinophil infiltration during early phase of allergen re-challenge.Here,we showed that eosinophil began to accumulate in the BALF at day2 post allergen re-challenge.Ablation of lung CD103+DCs in Langerin-DTR mice by DT injection resulted in

【Keywords】

allergic;eosinophil;airway;inflammation;accumulate;infiltration;challenge;modulate;unclear;recruit;

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