Identification of a novel terminally differentiated human dendritic cell lineage in psoriatic skin

【Author】

Daniel Korenfeld;Laurent Gorvel;adiel Munk;Josh Man;Marina Cella;David Donermeyer;Andras Schaffer;Thomas Tung;Caroline Mann;Paul Allen;Eynav Klechevsky;

【Abstract】

<正>Dendritic cells(DCs)are important in regulating both immunity and tolerance.Hence,we hypothesized that in psoriasis,an autoimmune disease characterized by autoreactive T cells,alterations in DC subsets may be causative.We undertook a comprehensive immunophenotyping approach analyzing the expression of 400immune-related proteins by human skin DCs.We found a novel population of

【Keywords】

autoimmune;alterations;immunity;differentiated;regulating;lineage;diseased;specialized;plaques;innovative;

References

To explore the background and basis of the node document

Springer Journals Database

Total: 0 articles

Similar documents

Documents that have the similar content to the node document

Springer Journals Database

Total: 0 articles