Phase Ⅱ vaccine clinical study with dendritic cells primed with glioma stem-like cells antigens against glioblastoma multiform of different molecular subtypes

【Author】

Feifei Luo;Yu Yao;Chao Tang;Wei Hua;Ying Mao;Liangfu Zhou;Yiwei Chu;

【Abstract】

<正>Dendritic cells(DC)-based immunotherapy has achieved promising results in treating tumor,but there are still considerable challenges in glioblastoma multiform(GBM).Thus we designed a double-blind,placebo-controlled phase II clinical trial post glioma resection surgery to assess the safety and effectiveness of DC vaccine loaded with glioma stem-like cells antigens(GSCA)in patients with newly diagnosed and

【Keywords】

glioma;Phase;vaccine;immunotherapy;placebo;treating;loaded;challenges;blind;subgroup;

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