Dendritic cells: holding the balance of immunity and tissue integrity


Roxane Tussiwand;


<正>Dendritic cells(DCs)can be subdivided in different subsets:conventional DC type-1(c DC1),c DC2 and plasmacytoid DCs(p DCs).Each subset has specialized functions and is required for protection against selected pathogens.p DCs are a major source of type-1 IFNs during viral infections.c DC1 are essential producers of IL-12 leading to IFN-g responses.c DC2 are a more heterogeneous subset;on one hand responsible for the production of IL-23,required for the induction of Th17 immunity,




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