Regulatory activity of IL-35 on human dendritic cell function

【Author】

Xi Chen;Shengnan Hao;Qianqian Shao;Zhonghua Zhao;Ying He;Wenjuan Gao;Haiting Mao;

【Abstract】

<正>IL-35 is a new member of the IL-12 family,existing as a heterodimer of IL-12A and Epstein-Barr virus-induced gene 3(Ebi3).IL-35 has anti-inflammatory properties and is produced by regulatory T cells and regulatory B cells,where it is required for optimal suppression of immune response.However,it is not clear whether IL-35plays an inhibitory role in human dendritic cells(DCs).In the present study,we

【Keywords】

suppression;Epstein;innate;maturation;stimulate;transducer;helper;modulating;inefficient;conclusion;

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