The mechanism of autophagy-mediated immune escape to porcine reproductive and respiratory syndrome virus

【Author】

Chunyan Wu;Enming Zhou;

【Abstract】

<正>The host infected by Porcine Reproductive and Respiratory Syndrome Virus(PRRSV)causes disorders of the adaptive immunity,with production of abundant non-neutralization antibodies and suppression of cellular immune response.It has been implicated the role of autophagy played in shuttling endogenous antigen into MHC class II antigen presentation pathway and further mediating immune response of the host.We demonstrated that PRRSV infection significantly increased the

【Keywords】

autophagy;porcine;immunity;abundant;suppression;presentation;endogenous;implicated;escape;infected;

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