Human BDCA1 dendritic cells are specialized for T follicular helper polarization

【Author】

Melanie Durand;Sebastian Amigorena;Elodie Segura;

【Abstract】

<正>Three DC subsets reside in human lymphoid organs:BDCA1 DC,BDCA3 DC and p DC.We previously showed that all human resident DC subsets have the ability to cross-present antigens to CD8 T cells.However,their ability to induce different CD4T cell responses remains unclear.Here we address the specialization of human resident DC subsets for CD4 T helper

【Keywords】

resident;specialized;specialization;helper;follicular;lymphoid;organs;unclear;cytokines;producing;

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