Monocyte-derived dendritic cells differentiated with IFN-α are able to induce cellular immune response to HIV

【Author】

Bruna Tereso Santillo;Denise da Silva Reis;Laís Teodoro da Silva;Alberto José da Silva Duarte;Telma Oshiro;

【Abstract】

<正>Dendritic cell based immunotherapy is a promising strategy for treating HIV patients.Alternatively to the conventional protocol for DC differentiation based on IL-4cytokine(IL4-DCs),some studies have suggested to obtain DCs by culturing monocytes in the presence of IFN type I(IFN-α),yielding the IFN-DC,already applied in cancer therapy.In our laboratory we used a vaccine protocol based on IL4-DCs for

【Keywords】

immunotherapy;cytokine;differentiated;vaccine;treating;yielding;phenotypic;cytometry;chemically;phenotype;

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