STING binding proteins regulate anti-viral immune responses

【Author】

Sheng Xu;Xuetao Cao;

【Abstract】

<正>STING is an endoplasmic reticulum adaptor,and the central adaptor in the innate immune response to DNA virus.After activation,STING activate both NF-κB and IRF3 pathways and induce production of type I interferons and inflammatory cytokines.However,the detailed regulatory mechanisms underlying STING signaling pathway are not fully illustrated.To identify new regulators in anti-DNA virus immune response,reverse-phase nanospray liquid chromatography–tandem mass

【Keywords】

endoplasmic;reticulum;innate;illustrated;activate;regulate;signaling;DNA;cytokines;tandem;

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