Batf3 dependent dendritic cells are crucial for development of primary biliary cholangitis

【Author】

Debby Reuveni;Patrick Leung;Oren Shibolet;Eric Gershwin;Ehud Zigmond;

【Abstract】

<正>Background:Primary Biliary Cholangitis(PBC)is a chronic autoimmune liver disease characterized by the presence of anti-mitochondrial antibodies(AMA)and hepatic antigen specific CD8+T cells,resulting in progressive cholestasis eventually leading to cirrhosis.DCs were identified in liver sections of PBC patients embedded in the damaged bile ducts,however,solid data evaluating their importance and function in

【Keywords】

cholangitis;autoimmune;cholestasis;cirrhosis;evaluating;progressive;eventually;sections;cytometry;histology;

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